Identification of inflammatory gene modules based on variations
of human endothelial cell responses to oxidized lipids

Method: Weighted Gene Co-Expression Network Analysis ( WGCNA )
                 Weighted Gene Coexpression Network Analysis


Peter S. Gargalovic, Minori Imura, Bin Zhang, Nima M. Gharavi, Michael J. Clark, Joanne Pagnon, Wen-Pin Yang, Aiqing He, Amy Truong, Shilpa Patel , Stanley F. Nelson , Steve Horvath, Judith A. Berliner, Todd G. Kirchgessner, and Aldons J. Lusis (2006) Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12741-6

Link to PNAS Paper Webpage: Here

Link to PNAS Paper PDF file: Here

 

Talk on this application

             PowerPoint Version

             PDF version

Other material regarding weighted gene co-expression network analysis

             Weighted Gene Co-Expression Network Page

             The weighted gene co-expression network analysis method is described in Theory Paper 1: Zhang and Horvath (2005)

             For a more mathematical description of weighted gene co-expression networks consider Theory Papers: Dong and Horvath (2007, 2008)

  


2008-11-12

Please send your suggestions and comments to: shorvath@mednet.ucla.edu