|2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002| 2001 |Before 2001 |

2013

    1. Chen Y, Huang K, Xue Z, Nakatsu, MN, Deng SX, Fan G. 2013. Identification of Novel Molecular Markers through Transcriptomic Analysis in Human Fetal and Adult Corneal Endothelial Cells.. Human Molecular Genetics (In Press)

2012

    1. Kun-Do Rhee, Juehua Yu, Carrie Yue Zhao, Guoping Fan, and Xian-Jie Yang. 2012. Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survival. Cell Death Dis. 2012 Nov 22;3:e427. PDF
    2. Cushman JD, Maldonado J, Kwon EE, Garcia AD, Fan G, Imura T, Sofronlew MV, Fanselow MS. 2012. Juvenile neurogenesis makes essential contributions to adult brain structure and plays a sex-dependent role in fear memories. Front Behav Neurosci. 2012;6:3. Epub 2012 Feb 2. PDF
    3. Hu G*, Huang K*, Yu J, Gopalakrishna-Pillai S, Kong J, Xu H, Liu Z, Zhang K, Xu J, Luo Y, Li S, Sun YE, Iverson LE, Xue Z, Fan G. Identification of miRNA Signatures during the Differentiation of hESCs into Retinal Pigment Epithelial Cells. PLoS One. 2012;7(7):e37224. Epub 2012 Jul 27. PDF
    4. Moore LD, Le T, Fan G. DNA Methylation and Its Basic Function. Neuropsychopharmacology. 2012 Jul 11. doi: 10.1038/npp.2012.112. [Epub ahead of print] PDF
    5. Li J, Jiang TX, Hughes MW, Wu P, Widelitz RB, Fan G, Chuong CM. Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1. J Invest Dermatol. 2012 Jul 5. doi: 10.1038/jid.2012.206. [Epub ahead of print] PDF
    6. Wu Z, Huang K, Yu J, Le T, Namihira M, Liu Y, Zhang J, Xue Z, Cheng L, Fan G. Dnmt3a regulates both proliferation and differentiation of mouse neural stem cells. J Neurosci Res. 2012 Oct;90(10):1883-91. doi: 10.1002/jnr.23077. Epub 2012 Jun 20. PDF
    7. Biswas A, Liu Y, Liu T, Fan G, Tang Y. Polyethylene glycol-based protein nanocapsules for functional delivery of a differentiation transcription factor. Biomaterials. 2012 Jul;33(21):5459-67. Epub 2012 Apr 21. PDF

2011

    1. F. Gomez-Pinilla, Y. Zhuang, J. Feng, Z. Ying and G. Fan. 2011. Exercise impacts brain-derived neurotrophic factor plasticity by engaging mechanisms of epigenetic regulation. European Journal of Neuroscience Volume 33, Issue 3,383:390 PDF
    2. Biswas, Anuradha; Joo, Kye-Il; Liu, Jing; Zhao, Muxun; Fan, Guoping; Wang, Pin; Gu, Zhen; Tang, Yi. 2011. Endoprotease-Mediated Intracellular Protein Delivery Using Nanocapsules. ACS Nano. 2011 Feb 22;5(2):1385-94. Epub 2011 Jan 26. PDF
    3. Le T, Kim KP, Fan G* (*corresponding author), Faull KF. 2011. A sensitive mass-spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples. Anal Biochem. 2011 May 15;412(2):203-9. Epub 2011 Jan 24.PMID: 21272560 PDF
    4. Dhawa S, Georgia S, Tschen S, Fan G and Bhushan A. Pancreatic beta cell identity is maintained by DNA methylation-mediated repression of Arx. Developmental Cell. 2011 Apr 19;20(4):419-29.
    5. Wang A, Huang K, Shen Y, Xue Z, Cai C, Horvath S, Fan G. 2011. Functional Modules Distinguish Human Induced Pluripotent Stem Cells from Embryonic Stem Cells. Stem Cells Dev. 2011 Nov;20(11):1937-50. PDF
    6. Huang K, Fan G. 2011. Epigenetic Modifications in Distinction: Histone versus DNA Methylation in ESCs. Cell Stem Cell. 2011 Jun 3;8(6):604-5. PDF
    7. Fan G, Tran J. 2011. X chromosome inactivation in human and mouse pluripotent stem cells. Hum Genet. 2011 Aug;130(2):217-22. PDF

2010

    1. Jin Zhong, Albert Chan, Leeron Morad, Harley I. Kornblum, Guoping Fan, and S. Thomas Carmichael. 2010. Hydrogel Matrix to Support Stem Cell Survival After Brain Transplantation in Stroke . Neurorehabil Neural Repair. 2010 Sep;24(7):636-44. Epub 2010 Apr 27. PDF
    2. Feng, J., Zhou, Y., Campbell, SL., Le, T., Li, E., Sweatt, JD., Silva, AJ., and Fan, G. 2010. Dnmt1 and Dnmt3a are required for the maintenance of DNA methylation and synaptic function in adult forebrain neurons. Nature Neuroscience.13:423-432 PDF
    3. Leah K Hutnick, Xinhua Huang, Tao-Chuan Loo, Zhicheng Ma and Guoping Fan. 2010. Repression of Retrotransposal elements in mouse embryonic stem cells is primarily mediated by DNA methylation-independent mechanism. The Journal of Biological Chemistry. 285(27):21082-91 PDF
    4. Huang K, Fan G. 2010. DNA methylation in cell differentiation and reprogramming: an emerging systematic view. Regenerative Medicine 5(4):531-44 PDF
    5. Tamar Dvash, Neta Lavon and Guoping Fan. 2010. Variations of X chromosome inactivation occur in early passages of female human embryonic stem cells. PLOS ONE. Jun 25;5(6):e11330 PDF
    6. Liao JL, Yu J, Huang K, Hu J, Diemer T, Ma Z, Dvash T, Yang XJ, Travis GH, Williams DS, Bok D, Fan G. 2010. Molecular Signature of Primary Retinal Pigment Epithelium and Stem-Cell derived RPE cells. Aug 13. Hum Mol Genet. 2010 Nov 1;19(21):4229-38. Epub 2010 Aug 13. PDF
    7. Laplant Q, Vialou V, Covington HE 3rd, Dumitriu D, Feng J, Warren BL, Maze I, Dietz DM, Watts EL, Iñiguez SD, Koo JW, Mouzon E, Renthal W, Hollis F, Wang H, Noonan MA, Ren Y, Eisch AJ, Bolaños CA, Kabbaj M, Xiao G, Neve RL, Hurd YL, Oosting RS, Fan G, Morrison JH, Nestler EJ. 2010. Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat Neurosci. V. 13: 1137-1143. PDF
    8. Liu B, Tahk S, Yee K., Fan G, Shuai K. 2010. The Ligase PIAS1 Restricts Natural Regulatory T-cell Differentiation by Epigenetic Repression. Science. 2010 Oct 22;330(6003):521-5. PDF
    9. Zhi-Gang Xue, Zhan-Ping Shi, Juan Dong, Ting-Ting Liao, Yan-Peng Wang,Xue-Ping Sun, Zheng-Jie Yan, Xiao-Qiao Qian, Yu-Gui Cui, Juan Chen,Jia-Yin Liu, and Guoping Fan. (2010) Evaluation of X-Inactivation Status and Cytogenetic Stability of Human Dermal Fibroblasts after Long-Term Culture. International Journal of Cell Biology. 289653. Epub 2010 Dec 27. PDF

2009

    1. Dvash, T., Fan, G., 2009. Epigenetic regulation of X-chromosome inactivation in human embryonic stem cells. Epigenetics 4:19-22 PDF
    2 Hutnick, L. and Fan, G. 2009. DNMT1. Targeted Proteins Database 1, [22563], 10.2970/tpdb.2009.221 PDF
    3. Hutnick, L., Golshi, P., Namihira, M., Xue, Z., Matynia, A., Yang, W., Silva, A. Schweizer, F., Fan, G. (2009). DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation Human Molecular Genetics 8(15):2875-2888 doi: 10.1093/hmg/ddp222. Published online May 10th, 2009 PDF
    4. Mason MJ, Fan G, Plath K, Zhou Q, Horvath S..2009. Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells BMC Genomics Jul 20;10(1):327 .PMID: 19619308 PDF
    5. Shen Y, Fouse SD, Fan G. 2009. Genome-Wide DNA Methylation Profiling: The mDIP-Chip Technology. Methods Mol Biol 2009;568:203-16.PMID: 19582429PDF
    6. Fan Z, Yamaza T, Lee JS, Yu J, Wang S, Fan G, Shi S, Wang CY. 2009. BCOR regulates mesenchymal stem cell function by epigenetic mechanisms. Nat Cell Biol Jul 5. PMID: 19578371 PDF
    7. Feng, J., Fan, G. 2009. The role of DNA methylation in the central nervous system and neuropsychiatric disorders. Int Rev Neurobiol V.89:67-84. (review) PMID: 19900616 PDF

2008

    1. Coskun, V., Wu, H., Blanchi, B., Tsao, S., Kim, K., Zhao, J., Biancotti, J-C., Hutnick, L., Krueger, RC., Fan, G., de Vellis, J., Sun, YE. (2008). Multipotent CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain. PNAS 2008 105(3):1026-31. PDF
    2. Fouse, S., Shen, Y., Pellegrini, M., Cole, S., Meissner, A., Van Neste, L., Jaenisch, R., Fan, G. (2008). Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, Polycomb binding and histone H3 lys4/lys27 trimethylation. Cell Stem Cell 2008 2(2):160-9 PDF Data
    3. Shen, Y., Matsuno, Y., Fouse, S., Rao, N., Root, S., Xu, R.H., Pellegrini, Riggs, A., Fan, G. (2008). X-inactivation in female human embryonic stem cells is in a non-random pattern and prone to epigenetic alterations. PNAS 2008 published online March 13, 2008, 10.1073/pnas.0712018105. PDF
    4. Wu, H., Kim, K.J., Mehta, K., Paxia, S., Sundstrom, A., Anantharaman, T., Kuraishy, A., Tri Doan, T., Ghosh, J., Pyle, A., Clark, A., Lowry, W., Fan, G., Baxter, T., Mishra, B., Sun, Y.E., Teitell, M.A. (2008). Copy Number Variant Analysis of Human Embryonic Stem Cells. Stem Cells Jun;26(6):1484-9. Epub 2008 Mar 27 PMID: 18369100 PDF
    5. Zeng, Q. An, S., Pan, Q., Xia, K., Xia, J., Zhang, Z., Sun, YE., ang Fan G. (2008). Efficient derivation of mesenchymal stem cells and neural precusor cells from human embryonic stem cells through teratoma formation. Progress in Biochemistry and Biophysics 35(12):1417-1424 PDF

2007

    1. Golshani, P., Hutnick, L., Schweizer, F., Fan, G. (2007). Conditional Dnmt1 deletion in dorsal forebrain disrupts development of somatosensory barrel cortex and thalamocortical long-term potentiation. Thalamus and Related System doi: 10.1017/S1472928807000222, Published online by Cambridge University Press 05 Mar 2007 PDF
    2. Feng, J., Fouse, S., Fan, G. (2007). Epigenetic regulation of neural gene expression and neuronal function. Pediatric Research 2007 May;61(5 Pt 2):58R-63R PDF

2006

    1. Shen, Y., Chow, J., Wang, Z., Fan, G. (2006). Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells. Human Molecular Genetics 2006 15(17):2623-35. PDF
    2. Lu Y-C., Song J., Cho H-Y, Fan G., Yokoyama K.K., and Chiu R. (2006). Cyclophilin A protects Peg3 from hypermethylation and inactive histone modification J. Biol. Chem. 2006 281:39081-7. Epub 2006 Oct 26. PDF

2005

    1. Feng, J., Chang, H., Li, E., and Fan. G. (2005) Dynamic expression of De novo DNA methyltransferases Dnmt3a and 3b in the central nervous system. Journal of Neuroscience Research. 79, 734-746. PDF
    2. Lyckman, AW., Fan, G., Rios, M., Jaenisch, R., Sur, M. (2005) Normal eye-specific patterning of retinal inputs to murine subcortical visual nuclei in the absence of brain-derived neurotrophic factor. Visual Science 22, 27-36. PDF
    3. He, F., Ge, W., Zhu, W., Becker-Catania, S., Martinowich, K., Wu, H., Coskun, V., Fan, G., deVellis, J., Sun, Y. (2005) A positive autoregulation loop of JAK-STAT signaling is part of the clock mechanism regulating astrogliogenesis. Nature Neuroscience. 8, 616-625. PDF
    4. Fan, G. and Hutnick, L. (2005) Methyl-CpG binding proteins in the nervous system (review paper). Cell Research 4, 255-61. PDF
    5. Fan, G., Martinowich, K., Chin, M., He, F., Fouse, S., Hutnick, L., Hattori, D., Ge, W., Shen, Y., Wu, H., ten Hoeve, T., Shuai, K., and Sun, Y. (2005) DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development 2005 Aug;132(15):3345-56. PDF

2004

    1. Chi, M.M., Fan, G., Fox, E.A. (2004) Increased short-term food satiation and sensitivity to cholecystokinin in neurotrophin-4 knock-in mice. Am J Physiol Regul Integr Comp Physiol. 2004 Nov;287(5):R1044-53. PDF

2003

    1. Endres, M., Fan, G., Hirt, L. and Jaenisch, R. (2003) Stroke damage in mice after knocking the NT4 gene into the BDNF locus. J. Cereb.Blood Flow. Metab. 23: 150-153. PDF
    2. Martinowich, K., Hatorri, D., Wu, H., Fouse, S., He, F., Hu, Y., Fan, G*., Sun, Y*. (*Corresponding authors) (2003) DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 302: 890-893. PDF

2002

    1. Ge, W., Martinowich, K., Wu, X., He, F., Miyamoto, A., Fan, G., Weinmaster, G., and Sun, YE. (2002) Notch signaling promotes astrogliogenesis via direct CSL mediated glial gene activation. Journal of Neuroscience Research 69: 848-860. PDF

2001

    1. Endres, M., Fan, G., Meisel, A., Dirnagl, U.and Jaenisch, R. 2001. (2001) Effects of cerebral ischemia in mice lacking DNA methyltransferase 1 in postmitotic neurons. Neuroreport 12: 3763-66. PDF
    2. Fan, G., Beard, C., Chen, R., Csankovszki, G., Sun, Y., Siniaia, M., Bates, B., Lee, P., Trumpp, A., Poon, C., Wilson, C., and Jaenisch, R. (2001) DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. Journal of Neuroscience 21: 788-797. PDF
    3. Sun, Y., Nadal-Vicens, M., Misono, S., Lin, MZ., Zubiaga, A., Hua, X., Fan, G., Greenberg, ME. (2001) Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 104: 365-376. PDF
    4. Fan, G., Siniaia, M., Poon, C., and Jaenisch, R. (2001) Effect of DNA hypomethylation on neural control of respiration: a genetic model. Adv. Exp. Med. Biol. 499: 195-200. Pub Med
    5. Akbarian, S., Bates, B., Liu, RJ., Skirball, SL., Pejchal, T., Coppola, V., Sun, LD., Fan, G., Kucera, J., Wilson, MA., Tessarollo, L., Kosofsky, BE., Taylor, JR., Bothwell, M., Nestler, EJ., Aghajania, GK., and Jaenisch, R. (2001) Neurotrophin-3 modulates noradrenergic neuron function and opiate withdrawl. Molecular Psychiatry 6: 593-604. PDF
    6. Rio, M., Fan, G., Fekete, C., Kelly, J., Bates, B., Lechan, RM., Jaenisch, J. (2001) Conditional deletion of brain-drived neurotrophic factor in the postnatal brain causes hyperactivity and obesity. Molecular Endocrinology. 15: 1748-1757. PDF

Before 2001

    1. Fan, G., Copray, S., Wong, E., Yan, Q., Jones, K., Walro, J., Jaenisch, R., and Kucera, J. (2000) Formation of the cranial proprioceptive system requires multiple neurotrophins. Developmental Dynamics 218: 359-370. PDF
    2. Endres, M, Fan, G (equal contribution), Hirt, L., Fujji, M., Liu, X., Jaenisch, R., and Moskowitz, M.A. (2000) Ischemic brain damage after selectively modifying BDNF or NT-4 expression in vivo. J. Cereb.Blood Flow. Metab. 20: 139-144. Pub Med
    3. Fan, G., Lei, X. , Cheng, H., Wang, X., Sun, B., and Hu, G. (2000) Targeted disruption of NDST-1 gene leads to pulmonary hypoplasia and neonatal respiratory distress in mice. FEBS. Letter 467: 7-11. PDF
    4. Fan, G., Egles, C., Sun, Y., Minichiello, L., Renger, J., Klein, R., Liu, G., and Jaenisch, R. (2000) Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities. Nature Neuroscience 3: 350-357. PDF
    5. Fan, G., Jaenisch, R., and Kucera, J. (1999) A role for p75 receptor in NT3 functioning during the development of limb proprioception. Neuroscience 90: 259-268. PDF
    6. Bates, B., Rios, M., Trumpp, A., Chen, C., Fan, G., Bishop, J.M., and Jaenisch, R. (1999) Neurotrophin-3 is required for proper cerebellar development. Nature Neurosci. 2: 115-7 . PDF
    7. Kucera, J., Fan, G., Walro, J., Copray, S., Tessarollo, L., and Jaenisch, R. (1998) Neurotrophin-3 and trkC in muscle are non-essential for the development of mouse muscle spindles. Neuroreport9: 905-909. PDF
    8. Kucera, J., Fan, G., Jaenisch, R., Linnarsson, S., and Ernfors, P. (1995) Dependence of developing group Ia afferents on neurotrophin-3. J. Comp. Neurol. 363: 307-320. PDF
    9. Hertzberg, T., Fan, G., Finley, J.C.W., Erickson, J.T., and Katz, D.M. (1994) BDNF supports mammalian chemoafferent neurons in vitro and following peripheral target removal in vivo. Dev. Biol. 166: 801-11. Pub Med
    10. Fan, G., and Katz, D.M. (1993) Non-neuronal cells inhibit the catecholaminergic differentiation of primary sensory neurons: role of leukemia inhibitory factor. Development 118: 83-93. PDF
|2011 |2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002| 2001 |Before 2001

 
2003-2011 UCLA Fan Lab